Native - Human Neutrophils
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Elastase, part of the serine protease superfamily, is a 30kDa protein expressed in neutrophil granules with a 267 amino acid residue. It undergoes posttranslational modification at both termini during processing of the enzyme. Reported to be present as a marker in IBD, it has also been implicated in congenital and cyclic neutropenia. Elastase reportedly could be used as a biomarker for the progression of cancer, specifically in colorectal cancer.
Elastase datasheetPrimary Sclerosing Cholangitis
Crohn's disease
Ulcerative Colitis
Systemic Lupus Erythematosus
Elastase is implicated in congenital and cyclic neutropenia Please log in to view certificates of analysis for this item
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- Dale, D.C. et al. (2000) Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia. Blood 96, 2317-22
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HLE
Elastase 2